David Kipling Selected Research

Phosphotransferases (Kinase)

12/2011	Investigating the role of c-Jun N-terminal kinases in the proliferation of Werner syndrome fibroblasts using diaminopyridine inhibitors.
9/2010	Gram-scale synthesis of the p38α MAPK-inhibitor VX-745 for preclinical studies into Werner syndrome.
6/2010	Evaluating the role of p38 MAP kinase in growth of Werner syndrome fibroblasts.
2/2010	Microwave-assisted synthesis of a pyrazolyl ketone library for evaluation as p38 MAPK inhibitors in Werner syndrome cells.
4/2007	The role of cellular senescence in Werner syndrome: toward therapeutic intervention in human premature aging.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

David Kipling Research Topics

Disease

19	Werner Syndrome (Werner's Syndrome) 04/2016 - 04/2003
14	Neoplasms (Cancer) 01/2023 - 05/2003
3	Melanoma (Melanoma, Malignant) 01/2023 - 05/2003
3	Genomic Instability 02/2013 - 04/2007
2	Communicable Diseases (Infectious Diseases) 01/2023 - 12/2011
2	Inflammation (Inflammations) 01/2020 - 10/2009
2	Wounds and Injuries (Trauma) 03/2018 - 02/2003
2	Carcinogenesis 01/2018 - 01/2004
2	Human Influenza (Influenza) 06/2015 - 01/2012
2	Liposarcoma 01/2014 - 03/2010
2	Progeria (Hutchinson Gilford Syndrome) 02/2013 - 04/2004
1	Autoimmune Diseases (Autoimmune Disease) 01/2023
1	Acute Disease 01/2022
1	COVID-19 01/2022
1	Parasitic Diseases (Parasitic Disease) 01/2020
1	Hyperplasia 01/2020
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2018
1	Monoclonal Gammopathy of Undetermined Significance 06/2015
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 06/2015
1	Nijmegen Breakage Syndrome 02/2015
1	Seasonal Allergic Rhinitis (Hay Fever) 09/2014
1	Allergic Rhinitis 09/2014
1	Rothmund-Thomson Syndrome (Syndrome, Rothmund-Thomson) 10/2013
1	Pneumococcal Pneumonia 12/2011
1	Lung Diseases (Lung Disease) 12/2011
1	Sarcoma (Soft Tissue Sarcoma) 03/2010
1	Lung Neoplasms (Lung Cancer) 01/2010
1	Breast Neoplasms (Breast Cancer) 01/2010
1	Vascular Calcification 10/2009
1	Ataxia Telangiectasia (Louis Bar Syndrome) 06/2009
1	Infections 02/2009
1	Insulin Resistance 01/2008

Drug/Important Bio-Agent (IBA)

13	p38 Mitogen-Activated Protein KinasesIBA 04/2016 - 11/2005
8	SB 203580IBA 01/2016 - 11/2005
7	Telomerase (Telomerase Reverse Transcriptase)IBA 03/2006 - 02/2003
5	Proteins (Proteins, Gene)FDA Link 06/2018 - 05/2003
5	Phosphotransferases (Kinase)IBA 12/2011 - 04/2007
4	5- amino- 1- (4- fluorophenyl)- 4- (3- (2,3- dihydroxypropoxy)benzoyl)pyrazoleIBA 01/2016 - 07/2008
3	AntibodiesIBA 01/2023 - 01/2020
3	Immunoglobulin E (IgE)IBA 01/2020 - 09/2014
3	KetonesIBA 01/2016 - 07/2008
3	DNA (Deoxyribonucleic Acid)IBA 08/2013 - 04/2003
3	VX-745IBA 09/2010 - 11/2009
3	Cyclin-Dependent Kinase Inhibitor p16IBA 01/2004 - 05/2003
2	Immunoglobulin G (IgG)IBA 01/2022 - 06/2015
2	MAP-kinase-activated kinase 2IBA 06/2015 - 01/2013
2	Immunoglobulins (Immunoglobulin)IBA 06/2015 - 06/2015
2	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 09/2014 - 08/2013
2	VaccinesIBA 12/2011 - 02/2009
2	doramapimodIBA 06/2010 - 11/2006
1	AntigensIBA 01/2023
1	Complementarity Determining Regions (Complementarity Determining Region)IBA 01/2023
1	AutoantigensIBA 01/2023
1	Yellow Fever Vaccine (Vaccine, Yellow Fever)FDA Link 01/2022
1	IgE Receptors (Fc epsilon RI)IBA 01/2018
1	BromidesIBA 06/2015
1	2-chloroquinolineIBA 06/2015
1	AcidsIBA 06/2015
1	3-pyridinylboronic acidIBA 06/2015
1	ParaproteinsIBA 06/2015
1	Immunoglobulin A (IgA)IBA 06/2015
1	Actins (F Actin)IBA 02/2015
1	GalactosidasesIBA 02/2015
1	Cysteine Dioxygenase (Dioxygenase, Cysteine)IBA 01/2014
1	Messenger RNA (mRNA)IBA 01/2014
1	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 08/2013
1	A-Form DNA (A-DNA)IBA 02/2013
1	Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)IBA 01/2012
1	Adenosine Triphosphate (ATP)IBA 09/2010
1	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2010
1	Ifosfamide FDA LinkGeneric 03/2010
1	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2010
1	Therapeutic UsesIBA 02/2010
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2010
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2009
1	Interleukin-8 (Interleukin 8)IBA 10/2009
1	CalciumIBA 01/2008
1	Phosphates (Orthophosphate)IBA 01/2008
1	VX (EDIM)IBA 09/2007
1	pyrazoleIBA 11/2006
1	CarbamatesIBA 11/2006
1	Urea (Carbamide)FDA LinkGeneric 11/2006
1	Mitogen-Activated Protein Kinase 14IBA 11/2006
1	CytokinesIBA 11/2005
1	Small Interfering RNA (siRNA)IBA 01/2004
1	Growth InhibitorsIBA 05/2003
1	beta-Galactosidase (Lactaid)IBA 02/2003

Therapy/Procedure

5	Therapeutics 06/2018 - 02/2003
1	Drug Therapy (Chemotherapy) 06/2018
1	Radiotherapy 06/2018